Document 1061
 DOCN  M9471061
 TI    Incidence of Kaposi's sarcoma (KS), non-Hodgkin's lymphoma (NHL), and
       other malignancies in a cohort of gay men with human immunodeficiency
       virus (HIV) infection (Meeting abstract).
 DT    9409
 AU    Lyter D; Bryant J; Thackeray R; Zhao P; Rinaldo C; Kingsley L; Univ. of
       Pittsburgh, Div. of Medical Oncology, Pittsburgh, PA
 SO    Proc Annu Meet Am Soc Clin Oncol; 13:A2 1994. Unique Identifier :
       AIDSLINE ICDB/94699998
 AB    Between October 1, 1984 and November 15, 1993, 1199 gay men were
       followed by the Pitt Men's Study, the Pittsburgh component of the MACS,
       a study of the natural history of HIV infection. The cohort included 769
       HIV seronegative (SN) participants and 430 who were either seropositive
       (SP) at enrollment or who seroconverted during the course of the study.
       Cancer incidence data were collected via semi-annual visits, phone
       interviews, medical records, and death certificates. 2344 person-years
       and 5708 person-years were contributed to the study by the SP and SN,
       respectively. In addition to 44 cases of KS in the SP and 14 NHL's (13
       in SP and 1 in SN), malignancies that occurred are shown in a table.
       Age-adjusted rates were calculated for both groups and compared with
       rates for the general population (GP). There were no differences between
       the SN and the GP. Rates of KS and NHL in the SP were 400 and 73 times
       higher (respectively) as compared to the GP. The total number of other
       cancers was significantly increased in the SP versus the GP, due to an
       increased rate of testicular cancer. There were no significant increases
       in rates of Hodgkin's disease, skin cancer or cancer of the anus in the
       SP.
 DE    Cohort Studies  Cross-Sectional Studies  HIV Infections/*EPIDEMIOLOGY
       Homosexuality/*STATISTICS & NUMER DATA  Human  Incidence  Lymphoma,
       AIDS-Related/*EPIDEMIOLOGY  Male  Neoplasms/*EPIDEMIOLOGY
       Pennsylvania/EPIDEMIOLOGY  Sarcoma, Kaposi's/*EPIDEMIOLOGY  Skin
       Neoplasms/*EPIDEMIOLOGY  MEETING ABSTRACT  MULTICENTER STUDY

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).